We are a Certified Treatment Site Specializing in Spravato™ (esketamine) and Ketamine IV Therapy

What Is Ketamine?

Ketamine is an FDA-approved medication for anesthesia that has been used safely every day in hospitals and emergency rooms world wide for over 50 years. In fact, the World Health Organization (WHO) has placed Ketamine on its list of "Essential Medicines."

Ketamine infusion therapy has been the object of scientific inquiry for those suffering from symptoms of depression, anxiety, PTSD, and pain syndromes since the early 2000's. It is currently believed that Ketamine plays a role in the NMDA receptor blocking pattern which increases the level of glutamate between neuronal pathways. This creates an environment where more optimal neuro-pathways are formed and strengthened. Ketamine infusion therapy allows for a reset of your brain and neuronal connections, effectively treating the chronic condition.

Many people who have lived their entire lives struggling with depression, anxiousness, fear, or pain are finding relief and truly living life again in a profound and meaningful way.

"Ketamine was life saving for me."

Spravato Nasal Spray

The FDA has now approved the first drug that can relieve depression in hours instead of weeks. In a recent article titled "FDA Approves Esketamine Nasal Spray For Hard-To-Treat Depression," NPR stated: 

"There has been a long-standing need for additional effective treatments for treatment-resistant depression, a serious and life-threatening condition," said Dr. Tiffany Farchione, acting director of the Division of Psychiatry Products in the FDA's Center for Drug Evaluation and Research, in a press release about the decision.

'This is potentially a game changer for millions of people,' said Dr. Dennis Charney, dean of the Icahn School of Medicine at Mount Sinai in New York.  'It offers a lot of hope.'"

Spravato (esketamine) Recommended Treatment Protocols / Pricing: 

Call for pricing / insurance coverage details.

Most insurance companies are now covering Spravato therapy; with a referral, our insurance coordinator can assist with your preauthorization. The recommended Spravato administration is typically twice a week for 4 weeks​.

Ketamine IV Therapy

Our experienced and caring medical practitioners at Evolve Health will provide Ketamine therapy  in micro-anesthetic doses to patients with a medical referral to help relieve treatment resistant depression, bi-polar depression, PTSD, obsessive compulsive disorder, anxiety, postpartum depression, migraines and chronic pain syndromes.

A series of infusions will be provided over the course of 12-14 days. We will customize the treatments depending on individual needs. Subsequent single maintenance infusions are typically required to control your symptoms. The benefits of infusion may last anywhere from 2 weeks to 3 months. Though not originally approved for these conditions by the FDA, it is SAFE OFF-LABEL use of this medication as we administer it under a controlled setting with a physician, anesthesia provider or nurse practitioner continually monitoring you.

“Recent data suggest that Ketamine, given intravenously, may be the most important breakthrough in antidepressant treatment in decades.”

– Thomas Insel MD, director of National Institute of Mental Health

Ketamine IV Therapy Recommended Treatment Protocols / Pricing:

Clinical experience has demonstrated that an initial series of infusions, followed by less frequent maintenance infusions, typically 1-3 months apart, provides the most effective, and lasting relief of symptoms. We'll customize each patient's treatment protocol to their unique condition and treatment needs as needed.

40-Minute Ketamine Infusion:

$495 per infusion. 

Infusions are indicated for depression, anxiety, PTSD, and OCD. We highly recommend 6 infusions over a 2-week period for optimal results - typically Monday, Wednesday, Friday.

2-Hour Ketamine Infusion:

$595 per infusion.

Infusions are often indicated for patients suffering from migraines, diabetic neuropathy, post-herpetic neuropathy, fibromyalgia, etc. We highly recommend 6 infusions over 6 consecutive days for optimal results.

4-Hour Ketamine Infusion:

$800 per infusion. 

Extended infusions are the most effective for CRPS other chronic pain syndromes. We highly recommend 5-10 infusions over 5-10 consecutive days.

Payment must be received for each treatment before the Ketamine Infusion Therapy can begin. Consult with your individual health savings account (HSA) or flexible spending account (FSA) administrators as most accept this innovative treatment.

Start feeling better with Ketamine--today!

A medical break-through for chronic depression relief without daily medication, or the wait.

If you or your loved one are suffering and conventional treatments haven't been successful, Ketamine therapy may be the answer. Call our Care Team today for more information or to schedule a consultation503.447.3285

What to Expect

Each patient's plan of care is unique, but typically follows a general protocol. The number and frequency of treatments is ultimately dictated by severity of symptoms, recurrence, and response to treatment. Some patients may experience significant improvement after one treatment, others may require multiple, and a small portion of patients may get little to no relief. 

Ketamine treatments are performed in our private suites to ensure patient comfort and minimize stimulation during the session. Dim lights and private flat screens displaying relaxing sounds and visuals provide a calming environment. During the entire treatment, you will be monitored by a nurse practitioner, anesthesia provider or a physician. 

Each patient’s experience is unique. After completion of the treatment you will be monitored for a short period of time to ensure your safety and comfort. Spravato patients will need to be monitored for 1-2 hours after administration. IV therapy patients will need to be monitored approximately 40 minutes post treatment. You will need to have arranged transportation home with a trusted individual. At home, we recommend that you continue to rest until the acute effects of the Ketamine and possible sedation have subsided. 

Talk To Your Provider:

( 1 )  You'll need to consult with your health provider about Ketamine therapy.  
( 2 )  We will need for you to obtain a ketamine treatment referral from your mental health provider. If you need a recommendation for a practitioner that is supportive of Ketamine therapy, please call us.
( 3 )  After receiving a referral, we will schedule your first evaluation and treatment. You will initially meet with one of our physicians, or nurse practitioners to review your medical history and discuss a treatment plan.


Explore the research. Scientific literature published in peer-reviewed journals supporting this groundbreaking new therapy:

How does Ketamine elicit a
rapid antidepressant response?

Current Opinion in Pharmacology

February 2015

Ketamine administration
in depressive disorders:

A systematic review and meta-analysis


July 2014

Ketamine as the prototype 

glutamatergic antidepressant:

Pharmacodynamic actions, and a systematic

review and meta-analysis of efficacy

Therapeutic Advances in Psychopharmacology

2014, Vol. 4(2) 75 –99

Explore articles about the effectiveness of Ketamine for treatment resistant depression.

Click to watch Ketamine Therapy Featured On:

Patient Resources